Can a brain zap and computer game sharpen aging minds?

NCT ID NCT05198726

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 2 times

Summary

This study tested whether combining a computer-based speed-of-processing training with a gentle electrical brain stimulation (alpha-tACS) could improve how quickly people with mild cognitive impairment process visual information. The trial planned to enroll 40 adults aged 65 and older, comparing the active stimulation plus training to a sham (placebo) stimulation plus training. The study was terminated early, so results are limited, but the goal was to see if this combination could boost thinking speed and potentially help with memory and other mental skills.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

alpha-tACS (a mild electrical brain stimulation device) and speed-of-processing training (a computer-based mental exercise)

What this could lead to

If it works, this could point toward a non-drug way to slow or improve thinking speed and memory in people with mild cognitive impairment.

What could go wrong

This was a small, early-stage trial that was terminated, so results are limited. The approach may not produce lasting or meaningful benefits, and brain stimulation can cause mild side effects like tingling or headache.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction persistent truncus arteriosus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Portucalense University

    Porto, 4200 - 072, Portugal