Scientists probe Brain's depression hub with targeted zaps

NCT ID NCT06266390

First seen Mar 07, 2026 · Last updated May 09, 2026 · Updated 8 times

Summary

This study looks at how a brain area called the subgenual cingulate responds to transcranial magnetic stimulation (TMS) in people with depression. Researchers will use MRI scans to see if TMS activates this region and how it changes over a 6-week treatment course. 50 adults with major or persistent depression will participate. The goal is to better understand how TMS works, not to test a new cure.

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Contacts and locations

Locations

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.