Scientists probe brain activity to map new depression treatments
NCT ID NCT05239780
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to understand how the brain processes rewards in people with depression. Researchers will record brain activity from epilepsy patients who also have depression while they play a gambling task. The goal is to identify abnormal brain signals that could guide future electrical stimulation treatments for depression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- electrical brain stimulation
- What this could lead to
- If successful, this could identify new brain targets for stimulation to treat depression.
- What could go wrong
- This is a very small, early study in epilepsy patients, not a treatment trial. It may not lead to a working therapy for depression.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Icahn School of Medicine at Mount Sinai
RECRUITINGNew York, New York, 100119, United States
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Other studies related to the condition(s) this trial covers.
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