Can brain signals predict freezing episodes in Parkinson's?
NCT ID NCT07748962
First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time
Summary
This study investigates how brain signals relate to freezing of gait and balance problems in people with Parkinson's disease. Participants, who already have a deep brain stimulation (DBS) device, will walk in a virtual reality home-like environment while their brain activity is recorded. Researchers will test different DBS settings to see how they affect walking and freezing episodes. The goal is to better understand the brain mechanisms behind these symptoms and potentially improve DBS therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Deep brain stimulation (DBS) with temporarily adjusted settings
- What this could lead to
- If successful, this could help tailor DBS settings to better prevent freezing of gait and improve balance in Parkinson's disease.
- What could go wrong
- This is a very small, early-stage study (5 participants) focused on understanding brain signals, not a treatment trial. Results may not apply to all patients, and temporary DBS adjustments carry risks like worsening symptoms.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Cleveland Clinic
Cleveland, Ohio, 44195, United States
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