Scientists peek inside the brain during Parkinson's surgery to understand movement control

NCT ID NCT06671626

ENROLLING_BY_INVITATION Knowledge-focused Sponsor: University of Texas Southwestern Medical Center Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study records brain activity from 125 Parkinson's patients during deep brain stimulation (DBS) surgery. Participants perform tasks that involve making decisions, stopping actions, or switching between actions. The goal is to understand how brain circuits control movement and how DBS helps improve symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Subcortical stimulation via deep brain stimulation electrodes
What this could lead to: If successful, this could reveal how deep brain stimulation improves movement control in Parkinson's disease, potentially guiding better therapies.
What could go wrong: This is an observational study during surgery, not a treatment trial. It is small and early-stage, so findings may not lead to direct patient benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

Locations

The University of Texas Southwestern Medical Center

Dallas, Texas, 75390, United States

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Other studies related to the condition(s) this trial covers.