Scientists peek inside brains of Parkinson's patients during surgery to understand action control

NCT ID NCT06671626

First seen Mar 25, 2026 · Last updated Jun 21, 2026 · Updated 11 times

Summary

This study records brain activity from 125 Parkinson's patients during deep brain stimulation (DBS) surgery. While patients perform tasks involving decision-making, stopping, or switching actions, researchers measure signals from the brain's surface and deep areas. The goal is to understand how the brain regulates actions and how DBS helps restore normal movement.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • The University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Subcortical stimulation via deep brain stimulation electrodes

What this could lead to

If successful, this could reveal how deep brain stimulation improves movement control in Parkinson's disease, guiding better treatments.

What could go wrong

This is an early-stage observational study during surgery, not a treatment trial. Results may not directly lead to new therapies, and findings are limited to Parkinson's patients undergoing DBS.

Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.