Could a nerve block or ear stimulation prevent brain damage after a hemorrhage?

NCT ID NCT07577739

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at 300 adults with a brain bleed from a ruptured aneurysm. It tests a non-invasive headband to monitor brain blood flow and two nerve treatments (a neck injection and ear stimulation) to see if they improve brain function. The goal is to find better ways to prevent delayed brain injury and guide care in the ICU.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Ropivacaine (local anesthetic) for cervical sympathetic block; transcutaneous auricular vagal nerve stimulation (taVNS) device
What this could lead to
If successful, this could lead to better, non-invasive ways to monitor brain health and prevent delayed complications after a brain bleed.
What could go wrong
This is an early-stage observational and feasibility study, not a treatment trial. The nerve stimulation and block are temporary and may not improve outcomes. Risks include side effects from the block (e.g., temporary Horner syndrome) and the stimulation.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UT Southwestern Medical Center - Clements University Hospital NSICU

    Dallas, Texas, 75390, United States

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