New brain scans aim to spot inflammation in MS and Alzheimer's
NCT ID NCT02649985
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study uses special PET scans to look for brain inflammation in people with multiple sclerosis (MS) and Alzheimer's disease. Researchers will compare two radioactive tracers, [F-18]PBR06 and [C-11]PBR28, to see which works better. Up to 250 participants, including healthy volunteers, will undergo imaging to understand how inflammation relates to disease severity and symptoms. The goal is to improve detection and monitoring of these neurological conditions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
[F-18]PBR06 and [C-11]PBR28 (radioactive tracers for PET scans)
What this could lead to
If successful, this could improve how we detect and monitor brain inflammation in MS and Alzheimer's, potentially leading to better diagnosis and treatment tracking.
What could go wrong
This is an early-phase imaging study, not a treatment trial. It may not directly lead to new therapies, and the tracers may not prove superior to existing methods.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham MS Center, 60 Fenwood Road
RECRUITINGBoston, Massachusetts, 02115, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••