Enema program may ease bowel troubles after rectal cancer surgery
NCT ID NCT06424522
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares a bowel management program that includes a retrograde rectal enema (RRE) against standard medical care (fiber, loperamide, pelvic floor therapy) for people with low anterior resection syndrome (LARS) after rectal cancer surgery. Researchers will enroll 80 adults with moderate to severe LARS who haven't improved with standard treatment. The goal is to see if adding the enema program better controls symptoms like fecal urgency, incontinence, and constipation.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- retrograde rectal enema (RRE)
- What this could lead to
- If successful, this could offer a more effective way to manage bowel symptoms like urgency and incontinence after rectal cancer surgery.
- What could go wrong
- This is a small, early-stage trial with only 80 participants, so results may not apply to everyone. The enema procedure may be uncomfortable or not work for some patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Ohio State University Comprehensive Cancer Center
RECRUITINGColumbus, Ohio, 43210, United States
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