Enema program may ease bowel troubles after rectal cancer surgery

NCT ID NCT06424522

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares a bowel management program that includes a retrograde rectal enema (RRE) against standard medical care (fiber, loperamide, pelvic floor therapy) for people with low anterior resection syndrome (LARS) after rectal cancer surgery. Researchers will enroll 80 adults with moderate to severe LARS who haven't improved with standard treatment. The goal is to see if adding the enema program better controls symptoms like fecal urgency, incontinence, and constipation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

retrograde rectal enema (RRE)

What this could lead to

If successful, this could offer a more effective way to manage bowel symptoms like urgency and incontinence after rectal cancer surgery.

What could go wrong

This is a small, early-stage trial with only 80 participants, so results may not apply to everyone. The enema procedure may be uncomfortable or not work for some patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Low Anterior Resection Syndrome rectal carcinoma rectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact