RECTAL CARCINOMA
Clinical trials for RECTAL CARCINOMA explained in plain language.
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Promising drug may shrink HER2+ colorectal tumors before surgery
Disease control Recruiting nowThis study tests a drug called zanidatamab given before surgery for people with HER2-positive colorectal cancer that has not spread widely. The goal is to see if the drug can shrink tumors and improve outcomes. About 38 adults will take part, and the study is currently recruiting…
Matched conditions: RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Emory University • Aim: Disease control
Last updated May 16, 2026 22:31 UTC
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New algorithm aims to keep chemo on schedule for cancer patients
Disease control Recruiting nowThis study tests a tool called PAGODA that helps doctors adjust chemotherapy doses ahead of time to avoid unplanned treatment delays. About 420 people with cancers of the digestive system (like colon, stomach, or esophageal cancer) will take part. The goal is to see if using this…
Matched conditions: RECTAL CARCINOMA
Phase: NA • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 16, 2026 22:27 UTC
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MRI-Guided strategy could spare rectal cancer patients unnecessary surgery
Disease control Recruiting nowThis study looks at whether using MRI scans early after chemotherapy can help personalize treatment for people with advanced rectal cancer. About 1,075 participants will be grouped as 'good' or 'poor' responders based on tumor shrinkage. Good responders will be randomly assigned …
Matched conditions: RECTAL CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle • Aim: Disease control
Last updated May 16, 2026 22:26 UTC
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New CT scanner could rival MRI for rectal cancer staging
Diagnosis Recruiting nowThis study compares a new type of CT scanner (PCD-CT) to standard MRI for determining how far rectal cancer has grown. About 200 adults with rectal cancer will receive both scans, and doctors will check if the CT is as accurate as MRI. If successful, this could offer a faster and…
Matched conditions: RECTAL CARCINOMA
Sponsor: Mayo Clinic • Aim: Diagnosis
Last updated May 06, 2026 16:03 UTC
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New enema program may ease bowel troubles after rectal cancer surgery
Symptom relief Recruiting nowThis study compares a bowel management program using a retrograde enema to standard medical care for people with bowel control problems after rectal cancer surgery. About 80 adults with moderate to severe symptoms will take part. The goal is to see if the enema program works bett…
Matched conditions: RECTAL CARCINOMA
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 16, 2026 22:31 UTC
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Hormone cream may help Women's vaginal health after cancer radiation
Symptom relief Recruiting nowThis study tests whether a vaginal cream containing the hormone DHEA can improve vaginal health in women who had radiation for gynecologic, anal, or rectal cancer. Radiation often causes dryness, burning, and pain. The trial will enroll 25 women to see if the cream is safe and to…
Matched conditions: RECTAL CARCINOMA
Phase: PHASE2 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 13, 2026 15:58 UTC
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New imaging tracer could light up tumors for better detection
Knowledge-focused Recruiting nowThis study is testing whether a new radioactive imaging agent can safely and clearly show tumors in people with many types of solid cancers. About 32 adults will receive a single injection of the agent and then have PET/CT scans to see where it goes in the body. The goal is to le…
Matched conditions: RECTAL CARCINOMA
Phase: EARLY_PHASE1 • Sponsor: Var2 Pharmaceuticals • Aim: Knowledge-focused
Last updated May 11, 2026 20:40 UTC