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MRI-Guided therapy could spare rectal cancer patients from unnecessary surgery

NCT ID NCT04749108

Recruiting now Disease control Sponsor: Institut du Cancer de Montpellier - Val d'Aurelle Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is for people with locally advanced rectal cancer. It tests whether using MRI scans early after chemotherapy can help doctors choose the best next step: surgery or more chemo with radiation. The goal is to improve cancer control and reduce side effects. About 1,075 participants will take part.

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Conditions

The condition(s) this trial relates to.

cancer rectal carcinoma rectal neoplasm rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED MALIGNANT NEOPLASM RECTAL CARCINOMA

Contacts and locations

Locations

  • Bordeaux Colorectal Institute

    RECRUITING

    Bordeaux, 33300, France

  • CAC Léon Bérard

    RECRUITING

    Lyon, France

  • CH Annecy

    NOT_YET_RECRUITING

    Annecy, Savoie, 74330, France

  • CH PAU

    RECRUITING

    Pau, Pyrénées-atlantiques, 64000, France

  • CHU Amiens

    RECRUITING

    Amiens, Picardie, 80054, France

  • CHU Besançon

    RECRUITING

    Besançon, Doubs, 25030, France

  • CHU Clermont-Ferrand

    RECRUITING

    Clermont-Ferrand, Puy De Dôme, 63000, France

  • CHU Rouen

    RECRUITING

    Rouen, Seine-Maritime, 76031, France

  • CHU de Bordeaux

    RECRUITING

    Bordeaux, Gironde, 33600, France

  • CHU de Lyon

    RECRUITING

    Lyon, Rhône, 69310, France

  • CHU de Nancy

    RECRUITING

    Vandœuvre-lès-Nancy, Lorraine, 54511, France

  • CHU de Nîmes

    RECRUITING

    Nîmes, 30029, France

  • CHU de Toulouse

    RECRUITING

    Toulouse, 31059, France

  • Centre Alexis Vautrin

    RECRUITING

    Nancy, Meurthe Et Moselle, 54519, France

  • Centre Antoine Lacassagne

    RECRUITING

    Nice, France

  • Centre Georges-François Leclerc

    NOT_YET_RECRUITING

    Dijon, 21079, France

  • Centre Oscart Lambret

    RECRUITING

    Lille, Nord, 59000, France

  • Chu Grenoble

    RECRUITING

    Grenoble, France

  • Chu Lille

    RECRUITING

    Lille, 59037, France

  • Hôpital Bicêtre

    RECRUITING

    Le Kremlin-Bicêtre, Val De Marne, 94270, France

  • Hôpital Diaconesses

    RECRUITING

    Paris, 75020, France

  • Hôpital Européen Georges-Pompidou

    RECRUITING

    Paris, 75015, France

  • Hôpital Européen de MARSEILLE

    RECRUITING

    Marseille, Bouches-du-rhône, 13003, France

  • Hôpital La Timone

    RECRUITING

    Marseille, 13005, France

  • Hôpital Nord de Marseille

    NOT_YET_RECRUITING

    Marseille, Bouches Du Rhône, 13015, France

  • Hôpital Saint-Antoine

    RECRUITING

    Paris, 75012, France

  • Hôpital Saint-Louis

    RECRUITING

    Paris, 75010, France

  • Insitut Régional du Cancer de Montpellier

    RECRUITING

    Montpellier, Hérault, 34298, France

  • Institut Paoli Calmettes

    RECRUITING

    Marseille, Bouches Du Rhône, 13009, France

  • Institut de Cancérologie de l'Ouest

    RECRUITING

    Saint-Herblain, 44800, France

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