LOW ANTERIOR RESECTION SYNDROME
Clinical trials for LOW ANTERIOR RESECTION SYNDROME explained in plain language.
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Breakthrough trial may let rectal cancer patients keep their rectum without surgery
Disease control Recruiting nowThis study tests whether a combination of chemotherapy and radiation before surgery (total neoadjuvant therapy) can help about half of rectal cancer patients achieve a complete response, allowing them to avoid surgery and preserve their rectum through a watch-and-wait strategy. T…
Matched conditions: LOW ANTERIOR RESECTION SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: National Cancer Center Affiliate of Vilnius University Hospital Santaros Klinikos • Aim: Disease control
Last updated May 15, 2026 11:56 UTC
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Stoma fluid recycling may stop post-surgery bowel chaos
Prevention Recruiting nowThis study tests a new way to prevent low anterior resection syndrome (LARS) — bowel urgency, leakage, and frequency — after rectal cancer surgery. 160 participants with a temporary ileal stoma will receive either their own intestinal fluid or water infused through the stoma befo…
Matched conditions: LOW ANTERIOR RESECTION SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: Pei-Rong Ding • Aim: Prevention
Last updated May 13, 2026 15:59 UTC
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New enema program may ease bowel troubles after rectal cancer surgery
Symptom relief Recruiting nowThis study compares a bowel management program using a retrograde enema to standard medical care for people with bowel control problems after rectal cancer surgery. About 80 adults with moderate to severe symptoms will take part. The goal is to see if the enema program works bett…
Matched conditions: LOW ANTERIOR RESECTION SYNDROME
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 16, 2026 23:36 UTC
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Bowel function showdown: parks vs. bacon surgery for rectal cancer
Symptom relief Recruiting nowThis study compares two surgical techniques (Parks and Bacon) for ultra-low rectal cancer to see which one results in better anal function and quality of life one year after surgery. About 256 adults with rectal cancer will be randomly assigned to one of the two procedures. The g…
Matched conditions: LOW ANTERIOR RESECTION SYNDROME
Phase: NA • Sponsor: Sixth Affiliated Hospital, Sun Yat-sen University • Aim: Symptom relief
Last updated May 04, 2026 16:30 UTC
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Why do some colon cancer survivors struggle with bowel control?
Knowledge-focused Recruiting nowThis study looks at why some people who had surgery for colorectal cancer develop bowel problems like urgency and incontinence. Researchers will compare 145 participants with and without these issues to find differences in body function and imaging. The goal is to group patients …
Matched conditions: LOW ANTERIOR RESECTION SYNDROME
Sponsor: Aalborg University Hospital • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC