New obesity drug BMF-650 enters first human safety trial
NCT ID NCT07223216
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage trial tests the safety and tolerability of a new drug called BMF-650 in 80 otherwise healthy adults who are overweight or obese. Participants receive either the drug or a placebo, and researchers monitor for side effects, vital signs, and how the drug moves through the body. The goal is to see if BMF-650 is safe enough to study further for weight control.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
BMF-650
What this could lead to
If successful, this could lead to a new medication for weight management in people with obesity.
What could go wrong
This is an early Phase 1 trial focused on safety, not weight loss. The drug may not prove effective or could have side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Medpace Clinical Pharmacology
Cincinnati, Ohio, 45227, United States