New obesity drug BMF-650 enters first human safety trial

NCT ID NCT07223216

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage trial tests the safety and tolerability of a new drug called BMF-650 in 80 otherwise healthy adults who are overweight or obese. Participants receive either the drug or a placebo, and researchers monitor for side effects, vital signs, and how the drug moves through the body. The goal is to see if BMF-650 is safe enough to study further for weight control.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
BMF-650
What this could lead to
If successful, this could lead to a new medication for weight management in people with obesity.
What could go wrong
This is an early Phase 1 trial focused on safety, not weight loss. The drug may not prove effective or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder Overweight Weight Loss

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Medpace Clinical Pharmacology

    Cincinnati, Ohio, 45227, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.