Tiny study tests blood flow cuffs and stepping machine for advanced Parkinson's
NCT ID NCT07221994
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This small pilot study tested whether using inflatable cuffs on the legs (blood flow restriction) during low-intensity stepping exercise could safely improve mobility and quality of life in people with advanced Parkinson's disease. Three participants exercised twice a week for 8 weeks on a Nu-Step machine while wearing the cuffs. The main goal was to check for side effects, with secondary goals of measuring motor symptoms and functional mobility.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Blood flow restriction (BFR) device and aerobic exercise via recumbent stepping
- What this could lead to
- If it works, this could offer a gentle exercise option to help people with advanced Parkinson's improve mobility and daily function.
- What could go wrong
- This is a very small pilot study (only 3 participants) with no control group, so results may not apply to others. The main goal was safety, not proof of effectiveness.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PARKINSON DISEASE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UCSF Health & Wellness Center (UCSF Mission Bay)
San Francisco, California, 94158, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Planning ahead: could a simple program transform Parkinson's care?
- Sound waves vs. Parkinson's: can ultrasound calm tremors and stiffness?
- Can a nudge in your chart unlock Life-Saving genetic clues?
- Can MRI reveal the Brain's response to deep brain stimulation?
- Can we outsmart Gaucher's hidden toll on lungs, bones, and brain?
- Could a brain disease change behavior years before diagnosis?