Listening to fistulas: sound may reveal hidden clots in dialysis patients

NCT ID NCT06411353

Recruiting now Knowledge-focused Sponsor: Mario Negri Institute for Pharmacological Research Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looks at whether the sounds made by blood flowing through an arteriovenous fistula (AVF) can tell doctors how healthy the fistula is. Researchers will use MRI and ultrasound to measure blood flow and compare it to the sounds recorded. If a clear link is found, it could lead to a simple, non-invasive way to monitor AVFs in people with end-stage kidney disease who need dialysis.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a non-invasive way to monitor fistula health using sound, potentially reducing complications in dialysis patients.
What could go wrong: This is a small, early-stage study with only 15 participants, so results may not apply broadly. The link between sound and blood flow may not be strong enough for clinical use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease congenital arteriovenous fistula Constriction, Pathologic end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

END-STAGE RENAL DISEASE

Contacts and locations

Locations

A.O. Papa Giovanni XXIII - U.O. Nefrologia e Dialisi
RECRUITING

Bergamo, Bergamo, 20147, Italy

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