Liver clot mystery: new study probes why blood clots form in cirrhosis

NCT ID NCT07439939

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how blood clotting works differently in the liver's portal vein compared to the rest of the body in people with liver cirrhosis. Researchers will take blood samples from 45 patients during a routine procedure called TIPS, which helps relieve high blood pressure in the liver. The goal is to better understand why some cirrhosis patients develop dangerous blood clots in the portal vein, which could lead to better prevention or treatment in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could improve understanding of why blood clots form in the liver's portal vein in cirrhosis, potentially guiding future prevention or treatment strategies.

What could go wrong

This is a small, early-stage observational study (45 participants) that measures biological markers, not a treatment trial. It may not lead directly to new therapies or apply to all cirrhosis patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver portal hypertension Thromboinflammation thrombotic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Paul Brousse

    RECRUITING

    Villejuif, 94800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••