New combo tackles tough leukemia

NCT ID NCT07283640

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 2 times

Summary

This early-phase study tests two drugs, blinatumomab and revumenib, given together to adults with a rare and aggressive form of acute lymphoblastic leukemia (ALL) that has a specific genetic change called KMT2A rearrangement. The main goal is to find a safe dose and understand side effects. The study includes people whose cancer has come back or not responded to treatment, as well as older or frail newly diagnosed patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • MD Anderson Cancer

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.