New drug duo takes on Hard-to-Treat leukemia

NCT ID NCT07355335

First seen Jan 22, 2026 · Last updated May 15, 2026 · Updated 18 times

Summary

This early-stage study tests whether combining two experimental drugs, ziftomenib and mezigdomide, is safe for teens and adults with a relapsed or treatment-resistant form of acute myeloid leukemia (AML) that has specific genetic changes. The goal is to find the best dose and watch for side effects. About 24 participants will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.