New trial tests smarter bladder cancer surgery to save Men's sexual health

NCT ID NCT05792722

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two surgical approaches for removing the bladder in men with bladder cancer: prostate capsule-sparing and nerve-sparing. The goal is to see which technique better preserves erectile function and urinary control. Seventy men will be randomly assigned to one of the two procedures and will complete questionnaires about their sexual and urinary health over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Prostate capsule-sparing radical cystectomy and nerve-sparing radical cystectomy

What this could lead to

If successful, this could show that a prostate-sparing surgery helps men maintain better erectile and urinary function after bladder removal, without increasing cancer risk.

What could go wrong

This is a small, early-stage trial (70 participants) comparing two surgical procedures. It is not testing a new drug or cure, and results may not apply to all bladder cancer patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Email: •••••@•••••

Locations

  • Johns Hopkins Hospital

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Sibley Memorial Hospital

    RECRUITING

    Washington D.C., District of Columbia, 20016, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••