Frailty check could personalize bladder cancer care for seniors
NCT ID NCT06138561
First seen Jun 27, 2026 ยท Last updated Jun 27, 2026
Summary
This study looks at whether a short survey called the Geriatric-8 can help doctors choose the best treatment for older patients with advanced bladder cancer who cannot take the strong chemotherapy drug cisplatin. Researchers will compare quality of life and side effects between two treatment approaches: one using a milder chemo followed by immunotherapy, and another using a newer drug combo. The goal is to find out which treatment works better for frail or at-risk patients.
What this could mean
Our plain-language read of the trial. This is informational only โ not medical advice or a prediction.
- Active substance
- Geriatric-8 survey (a frailty screening tool)
- What this could lead to
- If successful, this could help doctors personalize treatment decisions for older bladder cancer patients, improving quality of life and reducing side effects.
- What could go wrong
- This is an observational study that does not test a new drug, so it will not directly lead to a cure or new treatment. Results may not apply to all patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a Bag-Like device pull bladder tumors out whole?
- Can Pre-Surgery chemotherapy outsmart aggressive bladder cancer?
- Bladder cancer: a new combo aims to avoid radical surgery
- Could a simple urine test spare bladder cancer patients from chemotherapy?
- Can a new drug rally the immune system against Hard-to-Treat cancers?
- Can One-Piece tumour removal improve bladder cancer outcomes?