Frailty check could personalize bladder cancer care for seniors

NCT ID NCT06138561

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a short survey called the Geriatric-8 can help doctors choose the best treatment for older patients with advanced bladder cancer who cannot take the strong chemotherapy drug cisplatin. Researchers will compare quality of life and side effects between two treatment approaches: one using a milder chemo followed by immunotherapy, and another using a newer drug combo. The goal is to find out which treatment works better for frail or at-risk patients.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Geriatric-8 survey (a frailty screening tool)

What this could lead to

If successful, this could help doctors personalize treatment decisions for older bladder cancer patients, improving quality of life and reducing side effects.

What could go wrong

This is an observational study that does not test a new drug, so it will not directly lead to a cure or new treatment. Results may not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for BLADDER CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

stage IVb bladder cancer transitional cell carcinoma urinary bladder carcinoma Urinary Bladder Neoplasms urothelial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Dana-Farber Cancer Institute

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact