Can genes predict colorectal cancer drug success?
NCT ID NCT01822444
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 76 adults with advanced colorectal cancer to find genetic markers that might predict how well a combination of chemotherapy (FOLFOX) and the drug bevacizumab works. The goal was to understand which patients benefit most, not to test a new cure. Participants had a specific gene mutation (mutant K-ras) and received standard treatment while researchers analyzed their DNA and tumor responses.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beaumont Hospital
Dublin, Ireland
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Bon Secours Hospital
Cork, Ireland
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Cork University Hospital
Cork, Ireland
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Galway University Hospital
Galway, Ireland
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Gemeinschaftspraxis Haematologie/Onkologie
Lebach, Germany
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Kilnikum Ludwigsburg
Ludwigsburg, Germany
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Medizinische Klinik III, Universitaetsklinikum
Aachen, Germany
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Medizinische Klinik and Poliklinik Mainz
Mainz, Germany
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Onkologisches Zentrum
Deggendorf, Germany
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Private Practice Oncology
Speyer, Rhineland-Palatinate, Germany
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Sligo General Hospital
Sligo, Ireland
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St James Hospital
Dublin, Ireland
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St Vincent's University Hospital
Dublin, D4, Ireland
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The Adelaide and Meath Hospital, Dublin Incorporating the National Children's Hospital
Dublin, Ireland
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Univeritaetsmedizin Mannheim
Mannheim, Germany
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University Hospital Saarland
Homburg, Germany
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Waterford Regional Hospital
Waterford, Ireland