Can an existing skin drug heal rare, painful wounds?

NCT ID NCT07767864

First seen Aug 17, 2026 ยท Last updated Aug 17, 2026

Summary

This study tests whether bimekizumab, a drug already approved for other skin conditions, can help heal wounds in people with pyoderma gangrenosum (PG), a rare and painful skin disorder. Adults with PG will receive injections of bimekizumab every few weeks for 24 weeks. The main goal is to see if the drug leads to significant wound healing, which could offer a new treatment option for this challenging condition.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
bimekizumab, an experimental drug given as an injection under the skin
What this could lead to
If successful, this could point toward a new treatment option for pyoderma gangrenosum, a painful skin condition with few effective therapies.
What could go wrong
This is a small, early-phase study with only 15 participants, so results may not apply broadly. The drug is not yet approved for this condition and may cause side effects.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Oregon Health & Science University, Department of Dermatology

    Portland, Oregon, 97239, United States

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