New hope for painful skin ulcers: experimental drug enters human trials
NCT ID NCT07444684
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 study tests an injection called SHR-1139 in 20 adults with pyoderma gangrenosum, a rare condition causing painful skin ulcers. The goal is to see if the drug can completely close the ulcers and how safe it is. Researchers will also measure how the body processes the drug.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SHR-1139 injection
- What this could lead to
- If successful, this could point toward a new treatment option for pyoderma gangrenosum, a painful skin ulcer condition with limited therapies.
- What could go wrong
- This is a small early-phase trial with only 20 participants, so results may not apply to everyone. The drug may not work or could have side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Shandong First Medical University Affiliated Dermatology Hospital
Jinan, Shandong, 250022, China
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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