New injection aims to heal skin ulcers in rare disease

NCT ID NCT07337564

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This phase 2 trial tests an injection called SHR-1139 in 10 adults with ulcerative pyoderma gangrenosum, a rare skin condition that causes painful, open sores. The main goal is to see if the drug can completely close the target ulcer within 12 weeks. Researchers will also check for side effects and partial healing.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
SHR-1139 injection
What this could lead to
If it works, this could point toward a new treatment option for pyoderma gangrenosum, helping ulcers heal faster.
What could go wrong
This is a very small early-phase trial with only 10 people, so results may not apply broadly. The drug may not work or could cause side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Dermatology Hospital Affiliated to Shandong First Medical University

    Jinan, Shandong, 250000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.