New obesity drug's brain-body connection revealed in imaging study
NCT ID NCT05202353
First seen Jun 27, 2026 · Last updated Aug 05, 2026 · Updated 5 times
Summary
This early-stage study looks at how the experimental drug BI 456906 attaches to receptors in the liver and pancreas that control appetite and weight. About 30 adults with obesity will receive either BI 456906 or the approved weight-loss drug semaglutide for 17 weeks. Researchers use PET and MRI scans to measure receptor occupancy, aiming to understand how the drug works in the body.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Amsterdam UMC, location VUMC
Amsterdam, 1105 AZ, Netherlands
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