Can a heart drug tame stress inflammation?

NCT ID NCT06263452

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a single dose of the beta-blocker propranolol can reduce inflammation caused by psychological stress. Researchers will measure immune markers and brain activity in 120 healthy young adults before and after a stressful task. The goal is to understand the link between stress and heart disease risk.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Propranolol (a beta-blocker)

What this could lead to

If successful, this study could reveal how stress triggers inflammation and point toward new treatments to lower heart disease risk.

What could go wrong

This is an early-phase, small study (120 people) focused on understanding mechanisms, not testing a treatment. Results may not lead to direct therapies.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Social Neuroscience and Health Laboratory

    RECRUITING

    Chapel Hill, North Carolina, 27514, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact