Ultrasound-Guided Beta-Blockers: a new hope for septic shock?
NCT ID NCT07313605
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether using ultrasound to guide treatment with the beta-blocker esmolol is feasible in patients with septic shock. Septic shock is a life-threatening condition where infection causes very low blood pressure and a dangerously fast heart rate. The trial will enroll 100 adults and compare those receiving esmolol (to slow the heart) against standard care, monitoring for 90 days. The main goal is to see if a larger, definitive trial can be done successfully.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Esmolol (a beta-blocker drug given intravenously to slow heart rate)
What this could lead to
If this pilot succeeds, it could pave the way for a larger trial testing whether beta-blockers guided by ultrasound improve survival in septic shock.
What could go wrong
This is a small, early-phase feasibility study, not designed to prove benefit. Beta-blockers can be harmful if the heart is not well-filled or functioning poorly, and results may not generalize.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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