New IBS drug candidate camlipixant enters Mid-Stage trial
NCT ID NCT07519395
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This Phase 2b study tests camlipixant, an experimental drug, in 420 adults with moderate-to-severe irritable bowel syndrome (IBS) with diarrhea or mixed bowel habits. Participants receive either camlipixant or a placebo for 26 weeks. The main goal is to see if the drug reduces weekly abdominal pain. The trial also tracks other symptoms like bloating and discomfort.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
camlipixant
What this could lead to
If successful, camlipixant could offer a new treatment option to reduce abdominal pain and other symptoms in people with moderate-to-severe IBS-D and IBS-M.
What could go wrong
This is an early Phase 2b trial, so results may not confirm effectiveness. The drug may cause side effects, and not all participants may benefit. Larger studies are needed before it becomes available.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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GSK Investigational Site
RECRUITINGAnniston, Alabama, 36207, United States
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RECRUITINGGuntersville, Alabama, 35976, United States
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RECRUITINGMobile, Alabama, 36608, United States
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RECRUITINGSaraland, Alabama, 36571, United States
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RECRUITINGTempe, Arizona, 85284, United States
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RECRUITINGAnaheim, California, 92804, United States
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GSK Investigational Site
RECRUITINGChula Vista, California, 91910, United States
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RECRUITINGGarden Grove, California, 92845, United States
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GSK Investigational Site
RECRUITINGLancaster, California, 93534, United States
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GSK Investigational Site
RECRUITINGLancaster, California, 93534, United States
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GSK Investigational Site
RECRUITINGLos Angeles, California, 90015, United States
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GSK Investigational Site
RECRUITINGMurrieta, California, 92563, United States
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GSK Investigational Site
RECRUITINGPasadena, California, 91105, United States
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GSK Investigational Site
RECRUITINGSan Diego, California, 92103, United States
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GSK Investigational Site
RECRUITINGSan Diego, California, 92120, United States
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GSK Investigational Site
RECRUITINGSherman Oaks, California, 91403, United States
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RECRUITINGWest Hills, California, 91307, United States
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RECRUITINGAurora, Colorado, 80012, United States
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GSK Investigational Site
RECRUITINGColorado Springs, Colorado, 80907, United States
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RECRUITINGLone Tree, Colorado, 80124, United States
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GSK Investigational Site
RECRUITINGBrandon, Florida, 33511, United States
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GSK Investigational Site
RECRUITINGClearwater, Florida, 33756, United States
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GSK Investigational Site
RECRUITINGCoral Gables, Florida, 33134, United States
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GSK Investigational Site
RECRUITINGDoral, Florida, 33126, United States
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RECRUITINGHialeah, Florida, 33016, United States
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RECRUITINGHomestead, Florida, 33033, United States
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GSK Investigational Site
RECRUITINGJacksonville, Florida, 32258, United States
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RECRUITINGKissimmee, Florida, 34741, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33126, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33134, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33144, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33145, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33157, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33165, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33173, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33174, United States
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GSK Investigational Site
RECRUITINGMiami, Florida, 33186, United States
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GSK Investigational Site
RECRUITINGMiami Beach, Florida, 33141, United States
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GSK Investigational Site
RECRUITINGMiami Lakes, Florida, 33016, United States
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GSK Investigational Site
RECRUITINGMiami Springs, Florida, 33166, United States
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GSK Investigational Site
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GSK Investigational Site
RECRUITINGOcala, Florida, 34471, United States
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GSK Investigational Site
RECRUITINGOrlando, Florida, 32807, United States
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GSK Investigational Site
RECRUITINGOrlando, Florida, 32835, United States
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GSK Investigational Site
RECRUITINGPalm Harbor, Florida, 34684, United States
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GSK Investigational Site
RECRUITINGPembroke Pines, Florida, 33024, United States
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GSK Investigational Site
RECRUITINGPembroke Pines, Florida, 33026, United States
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GSK Investigational Site
RECRUITINGSunrise, Florida, 33351, United States
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GSK Investigational Site
RECRUITINGTampa, Florida, 33607, United States
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GSK Investigational Site
RECRUITINGTampa, Florida, 33607, United States
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GSK Investigational Site
RECRUITINGTampa, Florida, 33613, United States
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GSK Investigational Site
RECRUITINGTampa, Florida, 33614, United States
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GSK Investigational Site
RECRUITINGAtlanta, Georgia, 30328, United States
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GSK Investigational Site
RECRUITINGAtlanta, Georgia, 30342-5006, United States
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RECRUITINGDecatur, Georgia, 30033, United States
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GSK Investigational Site
RECRUITINGLawrenceville, Georgia, 30044, United States
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GSK Investigational Site
RECRUITINGUnion City, Georgia, 30291, United States
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RECRUITINGMeridian, Idaho, 83646, United States
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GSK Investigational Site
RECRUITINGMorton, Illinois, 61550, United States
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GSK Investigational Site
RECRUITINGOak Lawn, Illinois, 60453, United States
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GSK Investigational Site
RECRUITINGAmes, Iowa, 50010, United States
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GSK Investigational Site
RECRUITINGHouma, Louisiana, 70360, United States
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GSK Investigational Site
RECRUITINGBoston, Massachusetts, 02111, United States
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GSK Investigational Site
RECRUITINGFlint, Michigan, 48504, United States
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GSK Investigational Site
RECRUITINGChesterfield, Missouri, 48038, United States
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GSK Investigational Site
RECRUITINGHazelwood, Missouri, 63042, United States
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GSK Investigational Site
RECRUITINGMissoula, Montana, 59808, United States
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GSK Investigational Site
RECRUITINGHartsdale, New York, 10530, United States
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GSK Investigational Site
RECRUITINGNew Windsor, New York, 12553, United States
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GSK Investigational Site
RECRUITINGNew York, New York, 10016, United States
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GSK Investigational Site
RECRUITINGNorth Massapequa, New York, 11758, United States
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GSK Investigational Site
RECRUITINGRichmond Hill, New York, 11418, United States
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GSK Investigational Site
RECRUITINGRochester, New York, 14609, United States
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GSK Investigational Site
RECRUITINGCharlotte, North Carolina, 28210, United States
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GSK Investigational Site
RECRUITINGFayetteville, North Carolina, 28304, United States
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GSK Investigational Site
RECRUITINGGreenville, North Carolina, 27834, United States
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GSK Investigational Site
RECRUITINGRocky Mount, North Carolina, 27804, United States
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GSK Investigational Site
RECRUITINGSalisbury, North Carolina, 28144, United States
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GSK Investigational Site
RECRUITINGWinston-Salem, North Carolina, 27103, United States
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GSK Investigational Site
RECRUITINGBeavercreek, Ohio, 45431, United States
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GSK Investigational Site
RECRUITINGColumbus, Ohio, 43202, United States
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GSK Investigational Site
RECRUITINGMentor, Ohio, 44060, United States
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GSK Investigational Site
RECRUITINGNorman, Oklahoma, 73071, United States
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GSK Investigational Site
RECRUITINGTulsa, Oklahoma, 74104, United States
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GSK Investigational Site
RECRUITINGHarrisburg, Pennsylvania, 17110, United States
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GSK Investigational Site
RECRUITINGPittsburgh, Pennsylvania, 15236, United States
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GSK Investigational Site
RECRUITINGUniontown, Pennsylvania, 15401, United States
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GSK Investigational Site
RECRUITINGChattanooga, Tennessee, 37404, United States
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GSK Investigational Site
RECRUITINGChattanooga, Tennessee, 37412, United States
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GSK Investigational Site
RECRUITINGJohnson City, Tennessee, 37604, United States
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GSK Investigational Site
RECRUITINGKingsport, Tennessee, 37663, United States
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GSK Investigational Site
RECRUITINGKnoxville, Tennessee, 37909, United States
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GSK Investigational Site
RECRUITINGNashville, Tennessee, 37211, United States
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GSK Investigational Site
RECRUITINGCorsicana, Texas, 75110, United States
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GSK Investigational Site
RECRUITINGGeorgetown, Texas, 78628, United States
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GSK Investigational Site
RECRUITINGHarlingen, Texas, 785500, United States
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GSK Investigational Site
RECRUITINGHouston, Texas, 77081, United States
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GSK Investigational Site
RECRUITINGHouston, Texas, 77099, United States
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GSK Investigational Site
RECRUITINGMesquite, Texas, 75149, United States
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GSK Investigational Site
RECRUITINGMissouri City, Texas, 77459, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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GSK Investigational Site
RECRUITINGPearland, Texas, 77584, United States
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GSK Investigational Site
RECRUITINGSan Antonio, Texas, 78229, United States
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GSK Investigational Site
RECRUITINGOgden, Utah, 84403, United States
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GSK Investigational Site
RECRUITINGOgden, Utah, 84405, United States
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GSK Investigational Site
RECRUITINGSandy City, Utah, 84070, United States
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GSK Investigational Site
RECRUITINGLynchburg, Virginia, 24502, United States
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GSK Investigational Site
RECRUITINGPetersburg, Virginia, 23805, United States
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GSK Investigational Site
RECRUITINGRichmond, Virginia, 23226, United States
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