Engineered immune cells injected directly into brain to fight childhood tumors

NCT ID NCT04185038

First seen Jan 10, 2026 · Last updated Jun 11, 2026 · Updated 18 times

Summary

This early-phase study tests whether a new type of immune cell therapy, called CAR T cells, can be safely given directly into the brain or spinal fluid of children and young adults with certain aggressive brain tumors. The therapy uses the patient's own immune cells, which are modified in a lab to recognize and attack tumor cells. The goal is to see if this approach is safe and possible, and to gather early information on how well it works.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Seattle Children's Hospital

    RECRUITING

    Seattle, Washington, 98105, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.