AI reads brain scans to spot Parkinson's lookalikes

NCT ID NCT05913687

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests an AI tool called AIDP that analyzes MRI scans to help diagnose Parkinson's disease and two similar conditions (MSA and PSP). Researchers at 21 sites will compare the AI's diagnosis to that of movement disorder specialists. The goal is to see if the tool can improve diagnostic accuracy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

machine learning algorithm of imaging data

What this could lead to

If successful, this could provide doctors with a reliable, automated way to distinguish between Parkinson's disease and similar conditions using MRI scans.

What could go wrong

This is a diagnostic accuracy study, not a treatment trial. The tool may not outperform specialist diagnosis in real-world settings, and results may not apply to all patient populations.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

multiple system atrophy multiple system atrophy, parkinsonian type Parkinson disease progressive supranuclear palsy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Albany Medical College

    Albany, New York, 12020, United States

  • Augusta University

    Augusta, Georgia, 30912, United States

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

  • Centre for Addiction and Mental Health

    Toronto, M5T 2S8, Canada

  • Duke University Medical Center

    Durham, North Carolina, 22705, United States

  • Johns Hopkins University

    Lutherville, Maryland, 21093, United States

  • Massachusetts General Hospital

    Charlestown, Massachusetts, 02129, United States

  • Northwestern University

    Chicago, Illinois, 60611, United States

  • Ottawa Hospital Research Institute

    Ottawa, K1Y 4E9, Canada

  • Pennsylvania State University

    Hershey, Pennsylvania, 17033, United States

  • University of Alabama at Birmingham

    Birmingham, Alabama, 35294, United States

  • University of California San Diego

    La Jolla, California, 92037, United States

  • University of California San Francisco

    San Francisco, California, 94158, United States

  • University of Chicago

    Chicago, Illinois, 60637, United States

  • University of Florida

    Gainesville, Florida, 32611, United States

  • University of Kentucky

    Lexington, Kentucky, 40536, United States

  • University of Michigan

    Ann Arbor, Michigan, 48106, United States

  • University of Minnesota

    Minneapolis, Minnesota, 55414, United States

  • University of South Florida

    Tampa, Florida, 33613, United States

  • Wake Forest University

    Winston-Salem, North Carolina, 27157, United States

  • Washington University in St. Louis

    St Louis, Missouri, 63110, United States