Can a drug combo wake up 'Cold' tumors to immunotherapy?

NCT ID NCT05000294

First seen Nov 01, 2025 · Last updated May 13, 2026 · Updated 28 times

Summary

This study tests whether combining two drugs (atezolizumab and tivozanib) can help the immune system attack cancers that usually don't respond to immunotherapy, like certain prostate, pancreatic, and breast cancers. About 29 adults with advanced or metastatic disease who have already tried at least one prior treatment will receive the combination. The goal is to see if this approach can shrink tumors or slow cancer growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Florida

    Gainesville, Florida, 32608, United States

Conditions

Explore the condition pages connected to this study.