Heart failure patients may soon get fluid relief at home with a simple shot

NCT ID NCT06979726

Recruiting now Symptom relief Sponsor: University of Florida Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new approach for people with worsening heart failure who have too much fluid in their body. Instead of going to the hospital for IV treatment, patients get a water pill (furosemide) as a shot under the skin at home. The study will enroll 100 adults with heart failure and fluid overload to see if this home treatment is safe and works well. The goal is to reduce hospital visits and make care more convenient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: furosemide (a water pill given as a shot under the skin)
What this could lead to: If it works, this could allow some heart failure patients to get quick relief from fluid buildup at home instead of going to the hospital.
What could go wrong: This is a small early-phase study with only 100 people, so results may not apply to everyone. There is a risk of kidney injury or other side effects from the drug.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HEART FAILURE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Edema heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE VOLUME OVERLOAD

Contacts and locations

Locations

University of Florida
RECRUITING

Gainesville, Florida, 32608, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.