Can one aspirin a day beat two after joint surgery?

NCT ID NCT04295486

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study looks at whether taking 81 mg of aspirin once a day works just as well as taking it twice a day to prevent dangerous blood clots after hip or knee replacement surgery. About 5,500 adults having joint replacement will be randomly assigned to one of the two dosing schedules. The goal is to find the safest and most effective dose to prevent clots while reducing side effects like bleeding.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami Hospital

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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