One aspirin a day may be enough to prevent clots after joint surgery

NCT ID NCT04295486

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether taking 81 mg of aspirin once a day works just as well as taking it twice a day to prevent dangerous blood clots after hip or knee replacement surgery. About 5,500 adults having joint replacement will be randomly assigned to one of the two dosing schedules. The goal is to find the simplest, safest way to prevent clots without increasing side effects like bleeding.

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Conditions

The condition(s) this trial relates to.

venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Miami Hospital

    RECRUITING

    Miami, Florida, 33136, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact