New drug targets dangerous fat levels in blood

NCT ID NCT03783377

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-stage study tested a new medicine called ARO-APOC3 in healthy volunteers and people with severely high triglycerides or a rare genetic condition called familial chylomicronemia syndrome. The main goal was to check safety and how the drug moves through the body. The study involved 112 participants and has been completed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

familial chylomicronemia syndrome familial lipoprotein lipase deficiency hypertriglyceridemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site 10

    Papatoetoe, Auckland, 2025, New Zealand

  • Research Site 11

    Christchurch, 8011, New Zealand

  • Research Site 2

    Camperdown, New South Wales, 2050, Australia

  • Research Site 3

    Adelaide, South Australia, 5000, Australia

  • Research Site 4

    Perth, Washington, 6009, Australia

  • Research Site 5

    Sippy Downs, Queensland, Australia

  • Research Site 6

    Chicoutimi, Quebec, G7H 7K9, Canada

  • Research Site 7

    London, Ontario, N6A 5B7, Canada

  • Research Site 8

    Montreal, Quebec, H2W 1R7, Canada

  • Research Site 9

    Grafton, Auckland, 1010, New Zealand