Could a simple pain shot before surgery make stent recovery easier?

NCT ID NCT03638999

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This pilot study is testing whether a single injection of ketorolac (Toradol), given just before ureteral stent placement, can reduce pain and inflammation afterward. About 36 adults undergoing kidney stone surgery will be randomly assigned to receive either ketorolac or a placebo (saline). Researchers will measure pain levels on a 0–10 scale at several time points and also check if the study procedures are practical for a larger trial.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketorolac (Toradol) injection

What this could lead to

If it works, this could point toward a simple, low-cost way to reduce pain and discomfort for people with ureteral stents after kidney stone surgery.

What could go wrong

This is a very early, small pilot study with only 36 participants. The results may not be strong enough to change practice, and ketorolac carries risks like bleeding or kidney issues.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••