New drug could help ER patients with severe infection shock
NCT ID NCT06693726
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This pilot study tests whether giving angiotensin II early in the emergency department can help stabilize blood pressure in patients with septic shock. Twenty adults who need a standard drug called norepinephrine will receive angiotensin II as an add-on. The main goal is to see if this approach is feasible and safe in a busy ER setting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Angiotensin II
- What this could lead to
- If this works, it could provide a new way to quickly stabilize blood pressure in septic shock patients in the emergency department.
- What could go wrong
- This is a very small pilot study with only 20 patients, so results may not apply broadly. The drug may not work as hoped or could cause side effects like worsening organ function.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Iowa Hospitals and Clinics
RECRUITINGIowa City, Iowa, 52242, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Blood markers may foretell brain fog after sepsis
- Can tracking immune chaos in sepsis reveal new treatment targets?
- Blood clot score may predict organ damage in septic shock
- Could a key hormone be missing in septic shock?
- Could a simple mineral cut the need for powerful blood-pressure drugs in septic shock?
- Blood filter could shield vessels in septic shock