New obesity drug AMG 513 enters first human tests

NCT ID NCT06585462

Recruiting now Disease control Sponsor: Amgen Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial is testing a new drug called AMG 513 in 80 adults with obesity. The main goal is to see if the drug is safe and how the body handles it. Participants will receive either the drug or a placebo by injection, and researchers will monitor for side effects and measure drug levels in the blood.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: AMG 513
What this could lead to: If successful, this could lead to a new treatment option for obesity, helping people manage their weight.
What could go wrong: This is a very early Phase 1 trial with only 80 people, so it is primarily checking safety. The drug may not work for weight loss or could have side effects.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARDIOMETABOLIC DISEASE are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIOMETABOLIC DISEASE

Contacts and locations

Show contact details

Study contacts

Contact

Email: •••••@•••••

Locations

Anaheim Clinical Trials
RECRUITING

Anaheim, California, 92801, United States
Clinical Neuroscience Solutions - Jacksonville
RECRUITING

Jacksonville, Florida, 32256, United States
Clinical Pharmacology of Miami, LLC
RECRUITING

Miami, Florida, 33172, United States
Fomat Medical Research
RECRUITING

Oxnard, California, 93030, United States
Lillestol Research LLC
RECRUITING

Fargo, North Dakota, 58104, United States
New Horizon Research Center
RECRUITING

Miami, Florida, 33165, United States
Orange County Research Center
RECRUITING

Lake Forest, California, 92630, United States
Pinnacle Clinical Research
RECRUITING

Austin, Texas, 78757, United States
Rophe Adult and Pediatric Medicine/Sky Clinical Research Network Group
RECRUITING

Union City, Georgia, 30291, United States
Translational Clinical Research LLC
RECRUITING

Aventura, Florida, 33180, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.