New study aims to find better ways to track lung disease in PiMZ patients
NCT ID NCT06505603
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 80 adults with PiMZ alpha-1 antitrypsin deficiency and mild-to-moderate COPD over three years. Researchers will use CT scans and blood tests to measure lung density changes and look for biomarkers that could be used in future treatment trials. No new treatment is being tested; the goal is to improve how disease progression is tracked in this group.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could identify reliable biomarkers to speed up future drug trials for PiMZ patients with lung disease.
- What could go wrong
- This is an observational study with no treatment being tested. It may not lead to any direct benefit for participants or produce usable biomarkers.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Columbia University Irving Medical Center
NOT_YET_RECRUITINGNew York, New York, 10032, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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National Jewish Health
NOT_YET_RECRUITINGDenver, Colorado, 80206, United States
Contact Email: •••••@•••••
Contact
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University of Alabama at Birmingham
NOT_YET_RECRUITINGBirmingham, Alabama, 35233, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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University of California- Los Angeles
RECRUITINGLos Angeles, California, 90095, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Chicago
NOT_YET_RECRUITINGChicago, Illinois, 60637, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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