Hidden liver harm: new study seeks answers for rare disease

NCT ID NCT02014415

First seen Apr 30, 2026 · Last updated May 16, 2026 · Updated 3 times

Summary

This study looks at adults with Alpha-1 Antitrypsin Deficiency, a genetic condition that can cause lung and liver problems. Researchers want to find out how common liver injury is in these patients and what genetic or environmental factors might make it worse. About 120 participants will be followed for up to 5 years with liver biopsies and other tests, but no new treatment is being tested.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Boston University School of Medicine

    Boston, Massachusetts, 02118, United States

  • Saint Louis University

    St Louis, Missouri, 63104, United States

  • University of California

    San Diego, California, 92103, United States

Conditions

Explore the condition pages connected to this study.