St. Louis University

This study tests an oral testosterone pill called JATENZO in 20 men who have both low testosterone and chronic kidney disease. The goal is to see if the pill can raise testosterone levels and improve red blood cell counts, muscle strength, lean body mass, and sexual function. Par…

This phase 3 trial tests whether adding zoledronic acid (a bisphosphonate) to bone cement during surgery can lower the chance of a giant cell tumor of bone returning. About 120 people with primary tumors in their arms or legs will be randomly assigned to receive either standard s…

This study tests whether applying Prontosan antimicrobial gel to the skin during shoulder replacement surgery can reduce bacteria that might cause infections. It involves 60 adult men having their first shoulder replacement. Researchers will compare infection-related bacteria lev…

This study tests whether adding a non-opioid painkiller (ketorolac) to standard opioid pain medication can reduce the amount of opioids needed after preventive femur surgery. The study includes 60 adults with bone lesions from cancer who are getting a metal rod placed in the thig…

This study tests whether adding a short course of the steroid methylprednisolone to standard pain treatment can lower pain and reduce the need for opioids after ACL repair. About 90 people aged 13 to 50 having ACL surgery will take part. The goal is to find a safer way to manage …

This study looks at whether using the Headspace mindfulness app before surgery or chemoradiation can help people with endometrial or cervical cancer use fewer opioid painkillers. About 120 participants will be randomly assigned to use the app or not. The goal is to see if mindful…

This study tests a web-based training course called MAP for Coaches, designed to teach youth sport coaches how to prevent common muscle and bone injuries in young athletes. About 200 coaches of soccer, basketball, football, or volleyball will take the course. Researchers want to …