Promising new approach may slash recurrence of rare bone tumors
NCT ID NCT03295981
First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 27 times
Summary
This study tests whether applying a bisphosphonate drug directly to the surgical site can lower the chance of a giant cell tumor of bone returning. About 120 adults with a first-time tumor in an arm or leg will be randomly assigned to receive either standard surgery alone or surgery plus the drug. The main goal is to see if the drug reduces tumor recurrence without increasing infection risk.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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All India Institute of Medical Science
RECRUITINGNew Delhi, 110029, India
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Allegheny-Singer Research Institute
RECRUITINGPittsburgh, Pennsylvania, 15212, United States
Contact
Contact Email: •••••@•••••
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Beth Israel Deaconess Medical Center
RECRUITINGBoston, Massachusetts, 02215, United States
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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Indiana University
RECRUITINGIndianapolis, Indiana, 46202, United States
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Johns Hopkins University Hospital
RECRUITINGBaltimore, Maryland, 21287, United States
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Massachusetts General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
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McGill University Health Centre
COMPLETEDMontreal, Quebec, H3G 1A4, Canada
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Saint Louis University
RECRUITINGSt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California - Los Angeles
RECRUITINGLos Angeles, California, 90404, United States
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Contact
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University of Iowa
RECRUITINGIowa City, Iowa, 52242, United States
Contact Email: •••••@•••••
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University of Kansas
COMPLETEDOverland Park, Kansas, 66211, United States
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University of Oklahoma
RECRUITINGOklahoma City, Oklahoma, 73104, United States
Contact
Contact Email: •••••@•••••
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University of Washington
COMPLETEDSeattle, Washington, 98195, United States
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Wake Forest University
COMPLETEDWinston-Salem, North Carolina, 27157, United States
Conditions
Explore the condition pages connected to this study.