New hope for rare bone tumor: XGEVA shows promise in chinese study

NCT ID NCT04586660

First seen Oct 31, 2025 · Last updated May 13, 2026 · Updated 25 times

Summary

This study tests the drug XGEVA (denosumab) in Chinese adults and teens aged 12 and older with giant cell tumor of bone, a rare but serious bone growth. The goal is to see if the drug can shrink tumors or stop them from getting worse. Participants receive XGEVA and are monitored for tumor response and disease progression.

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Contacts and locations

Locations

  • Beijing Jishuitan Hospital

    Beijing, Beijing Municipality, 100035, China

  • Harbin Meidical University Cancer Hospital

    Harbin, Heilongjiang, 150000, China

  • National Taiwan University Hospital

    Taipei, 10002, Taiwan

  • Peking University Peoples Hospital

    Beijing, Beijing Municipality, 100044, China

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510663, China

  • Taipei Veterans General Hospital

    Taipei, 11217, Taiwan

  • Tangdu Hospital of Air Force Medical University

    Xi'an, Shaanxi, 710032, China

  • The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, 350005, China

  • The Second Affiliated hospital of Zhejiang University School of Medicine

    Hangzhou, Zhejiang, 310052, China

  • The Third Affiliated Hospital Of Southern Medical University

    Guangzhou, Guangdong, 510630, China

Conditions

Explore the condition pages connected to this study.