Blood test may replace scans and biopsies for rare bone tumor

NCT ID NCT07609277

First seen May 27, 2026 · Last updated Jun 17, 2026 · Updated 4 times

Summary

This study looks at whether a blood test for a substance called TRACP-5b can help doctors diagnose and monitor giant cell tumor of bone (GCTB), a rare but aggressive bone tumor. Currently, patients need regular CT or MRI scans and sometimes invasive biopsies to check if the tumor has returned. Researchers will measure TRACP-5b levels in blood samples from 70 adults with GCTB during routine visits and compare them to imaging and biopsy results. If successful, this could lead to a simpler, less invasive way to detect recurrences earlier.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • First Department of Orthopaedic Surgery, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czechia

    RECRUITING

    Brno, 60200, Czechia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

bone giant cell tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.