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Blood test may spot bone tumor return without scans or needles

NCT ID NCT07609277

Recruiting now Diagnosis Sponsor: St. Anne's University Hospital Brno, Czech Republic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study is testing whether a blood test for a substance called TRACP-5b can help doctors diagnose and monitor giant cell tumor of bone, a rare but aggressive tumor that often comes back after treatment. Researchers will take blood samples from 70 patients during routine checkups and compare the results with scans and biopsies. If it works, this test could make follow-up care easier and less invasive.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
TRACP-5b blood test
What this could lead to
If successful, this blood test could offer a simpler, less invasive way to detect tumor recurrence and monitor disease activity in giant cell tumor of bone.
What could go wrong
This is a small, early observational study. The biomarker may not prove reliable enough to replace standard imaging or biopsies, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone giant cell tumor

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DISEASE SURVEILLANCE AND MONITORING GIANT CELL TUMOR OF BONE TARTRATE-RESISTANT ACID PHOSPHATASE 5B TRACP-5B

Contacts and locations

Locations

  • First Department of Orthopaedic Surgery, St. Anne's University Hospital and Faculty of Medicine, Masaryk University, Brno, Czechia

    RECRUITING

    Brno, 60200, Czechia

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