Gut bacteria supplement shows promise for weight loss

NCT ID NCT06964919

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested whether a heat-killed probiotic called Akkermansia muciniphila Akk11 could help overweight or obese adults lose weight and improve their metabolism. 61 participants took either the probiotic or a placebo capsule daily for 12 weeks, while following a low-carb diet. Researchers measured changes in body weight, BMI, waist size, and blood fats like cholesterol.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Heat-killed Akkermansia muciniphila Akk11 probiotic capsules
What this could lead to
If it works, this could offer a natural probiotic supplement to help with weight loss and improve cholesterol levels in overweight people.
What could go wrong
This is a small, early-stage trial with only 61 participants. The effects may be modest, and results might not apply to everyone. As a dietary supplement, it is not a substitute for lifestyle changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The School of Food and Bioengineering, Henan University of Science and Technolog

    Luoyang, Henan, 471000, China

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