Gut bacteria supplement shows promise for weight loss

NCT ID NCT06964919

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed trial tested whether a heat-killed probiotic called Akkermansia muciniphila Akk11 could help overweight or obese adults lose weight and improve their metabolism. 61 participants took either the probiotic or a placebo capsule daily for 12 weeks, while following a low-carb diet. Researchers measured changes in body weight, BMI, waist size, and blood fats like cholesterol.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Heat-killed Akkermansia muciniphila Akk11 probiotic capsules

What this could lead to

If it works, this could offer a natural probiotic supplement to help with weight loss and improve cholesterol levels in overweight people.

What could go wrong

This is a small, early-stage trial with only 61 participants. The effects may be modest, and results might not apply to everyone. As a dietary supplement, it is not a substitute for lifestyle changes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The School of Food and Bioengineering, Henan University of Science and Technolog

    Luoyang, Henan, 471000, China