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Pollution may worsen pregnancy dangers for heart patients

NCT ID NCT07164157

Knowledge-focused Sponsor: Wei Huang Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
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First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study looked at 1,200 pregnant women with pulmonary hypertension (high blood pressure in the lungs) to see if long-term exposure to air pollution raises the risk of serious pregnancy complications like heart failure or death. Researchers analyzed medical records and residential air quality data. The goal was to understand how environmental factors affect this high-risk group, which had not been studied before.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

1,200 people

The number who actually took part.

Started

Jan 2013

Finished

Dec 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Pregnant women with pulmonary hypertension(PH) who attended major medical centers included in this study from January 2013 to December 2022. Our study includes all types of pregnant women with PH, primarily those who with congenital heart disease-associated PH, followed by those with left heart disease-associated PH.

Ages

18 to 50 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Pregnant women with pulmonary hypertension who attended major medical centers included in this study from January 2013 to December 2022. * Complete medical records available; ② Pulmonary artery systolic pressure ≥ 35 mmHg by echocardiography or a confirmed diagnosis of pulmonary hypertension by right heart catheterization; ③ Residential address information available at the city (district, county) level or higher. Exclusion Criteria: * ① Unclear diagnosis and completely missing address information; * Incomplete medical records; ③ Lost to follow-up during pregnancy or within six weeks postpartum.

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Conditions

The condition(s) this trial relates to.

heart failure Premature Birth pulmonary arterial hypertension pulmonary hypertension

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Air pollution Maternal outcome Pulmonary arterial hypertension

Contacts and locations

Locations

  • The First Affiliated Hospital, Chongqing Medical University

    Chongqing, Chongqing Municipality, 400016, China

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Other studies related to the condition(s) this trial covers.