AI helps pacemaker find the sweet spot for failing hearts

NCT ID NCT07206602

Recruiting now Disease control Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether using artificial intelligence to guide a heart pacing procedure (left bundle branch area pacing) can improve heart function more than the standard approach. Researchers will compare AI-guided pacing to conventional pacing in 224 adults with heart failure. The main goal is to see if more patients have a significant increase in their heart's pumping ability after six months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Left bundle branch area pacing (a heart pacing procedure) with AI guidance
What this could lead to: If successful, this could lead to a more effective pacing method for heart failure patients, improving heart function and quality of life.
What could go wrong: This is a small pilot study, so results may not apply to all patients. The AI guidance may not significantly improve outcomes over standard pacing, and the procedure carries typical risks of heart device implantation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

heart failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEART FAILURE

Contacts and locations

Locations

Mayo Clinic in Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

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Other studies related to the condition(s) this trial covers.