Tiny study probes gene link to kidney stones
NCT ID NCT04430426
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how a specific gene change (AGXT) affects oxalate production in people who have had calcium oxalate kidney stones. Four participants will eat a low-oxalate diet for five days and then receive an intravenous dose of glycolate. Researchers will measure oxalate levels in blood and urine to understand how the gene change influences stone risk.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
glycolate administered intravenously
What this could lead to
If successful, this could help identify people at higher risk for kidney stones and point toward new prevention strategies.
What could go wrong
This is a very small, early study with only 4 participants. It is designed to gather knowledge, not to test a treatment, so direct benefits are unlikely.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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