Can acupuncture and ice chips beat chemo nerve damage?

NCT ID NCT04505553

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This phase 2 trial looked at whether adding acupuncture and acupressure to oral cryotherapy (sucking on ice chips) can reduce nerve pain caused by oxaliplatin chemotherapy in people with gastrointestinal cancers. 78 patients were split into two groups: one got cryotherapy alone, the other got cryotherapy plus acupuncture and acupressure. The study measured changes in nerve pain severity over three months using a standard questionnaire.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Acupuncture, acupressure, and oral cryotherapy

What this could lead to

If it works, this could offer a drug-free way to ease nerve pain from chemotherapy for people with gastrointestinal cancers.

What could go wrong

This is a small pilot study with only 78 participants, so results may not apply to everyone. The added benefit of acupuncture over cryotherapy alone may be small or none.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Adenoma, Islet Cell anal carcinoma anus neoplasm appendiceal neoplasm appendix carcinoma bile duct carcinoma biliary tract cancer carcinoma of esophagus carcinoma of liver and intrahepatic biliary tract colon carcinoma colonic neoplasm digestive system cancer digestive system carcinoma digestive system neoplasm digestive system neuroendocrine neoplasm digestive system neuroendocrine tumor, grade 1/2 Esophageal Neoplasms exocrine pancreatic carcinoma gastric carcinoma gastric neoplasm hepatocellular carcinoma pancreatic adenocarcinoma pancreatic neoplasm pancreatic neuroendocrine tumor rectal carcinoma rectal neoplasm small intestine carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States