Zhongshan Ophthalmic Center, Sun Yat-sen University

This trial investigates whether people with diabetic macular edema can safely monitor their vision and eye health at home instead of making frequent hospital visits. Participants use a home vision tester and a portable eye scanner every four weeks, with results sent to their doct…

This study tests whether placing a capsular tension ring (CTR) during cataract surgery helps keep the artificial lens more stable in people with retinitis pigmentosa (RP). Each of the 88 participants will get the ring in one eye, while the other eye serves as a comparison. Resear…

This study tests if a direct injection of the drug rituximab into eye tumors works as well as standard radiation therapy for a slow-growing eye lymphoma (MALT lymphoma). The goal is to control the disease with fewer complications. About 108 adults with early-stage eye lymphoma wi…

This early-stage trial tests a gene therapy called ZVS106e for Stargardt disease, a genetic condition that causes vision loss. Nine participants will receive a single injection of the drug under their retina. The main goal is to check safety over 52 weeks, not yet to prove it wor…

This study tests whether applying 5-fluorouracil (5-FU) during tear duct surgery can improve success for people with a small tear sac and blocked tear ducts. The trial will enroll 100 adults who need endoscopic dacryocystorhinostomy (En-DCR). Half will get standard surgery plus a…

This study tests a smartphone app that uses artificial intelligence to detect 16 different eye diseases from photos taken with the phone. The AI works entirely on the device, so no internet is needed. Researchers will compare its accuracy to eye doctors and see if non-medical use…

This study tests whether a web-based visual training program can improve vision in children aged 4-12 who had surgery for a rare lens dislocation condition called congenital ectopia lentis. Over 3 months, 82 children will use the training software for 30 minutes daily. Researcher…

This study tests a new painkiller called Anrikefon in 204 adults having eye surgery under general anesthesia. Researchers want to see if it controls pain as well as the standard drug nalbuphine, but with fewer side effects like drowsiness. Participants get one dose during surgery…

This study is following 5,000 adults aged 65 and older to learn how eye diseases develop and progress over time. Researchers will collect detailed health information, eye exams, and biological samples to build a comprehensive database. The goal is to create a personalized risk pr…

This study looks at 300 people having cataract surgery to see if where the surgeon places the phacoemulsification tip (the tool that breaks up the cataract) affects early healing. Researchers will use a special camera during surgery to track the tip's location and then measure co…

This study will use advanced eye scans (OCT and OCTA) to compare the structure and blood flow of the choroid and retina in people with two main types of glaucoma: primary angle-closure disease and primary open-angle glaucoma. Researchers aim to better understand how these conditi…

This study looks at a new way to provide eye care to children in rural China. It will involve about 20,000 kids aged 3 to 18 from schools in several counties. The goal is to see if a coordinated program across local health centers and schools can improve eye screening rates and h…

This study follows 73 people with congenital ptosis (droopy eyelids) who are already scheduled for a specific surgery. Researchers will check their vision and ask about their quality of life before surgery and at 1, 3, and 6 months after. The goal is to see if the surgery improve…

This study uses special cameras to watch how eye tissues heal after minimally invasive glaucoma surgery. Researchers will follow 300 glaucoma patients to measure changes in the eye's drainage angle over time. The goal is to learn more about healing patterns and help improve futur…