Zhongshan Ophthalmic Center, Sun Yat-sen University

This study tests special glasses called D.D.C dual-control lenses to see if they can slow down worsening nearsightedness (myopia) in children aged 6 to 14. Over 24 months, 316 kids will wear either the new lenses or standard glasses. The goal is to measure changes in eye prescrip…

This trial tests two different needle insertion spots during YAMANE surgery, a procedure to fix a lens in the eye for children with congenital ectopia lentis (a condition where the eye's lens is out of place). Researchers will compare how accurate the lens placement is and how we…

This study tests two different needle insertion spots (2mm vs 2.5mm from the eye's edge) for a special lens implant surgery in children aged 4-18 with congenital ectopia lentis, a condition where the eye's natural lens is out of place. The goal is to see which spot gives better v…

This trial tests whether an enhanced monofocal intraocular lens, set for monovision (one eye for distance, one for near), improves vision without glasses in people with both cataracts and high myopia. Sixty-six participants will receive the lens in both eyes and be followed for o…

This study tests whether sending regular health education messages about eye care to parents via WeChat can improve how children use their eyes and slow or prevent nearsightedness. About 1,330 third-grade students in China will take part, with their guardians receiving the messag…

This study compares a new eyelid support plate to a standard glass rod for eyelid massage in people with dry eye from meibomian gland dysfunction. 142 adults will receive either the new device or standard massage, plus eye drops, over 8 weeks. The goal is to see which method bett…

This study compares two behavioral interventions—Baduanjin (a gentle 10-15 minute exercise) or laughter exercises using a smartphone app—plus artificial tears, against artificial tears alone for treating dry eye disease. About 540 adults aged 18-45 with moderate dry eye will part…

This study tests two different methods of centering laser eye surgery (SMILE) in people with nearsightedness and a large angle kappa—a natural offset between the visual axis and pupil center. One method uses a 50% correction, the other 100%. Researchers want to see which approach…

This trial tests whether a small adjustment during SMILE laser surgery—compensating for the eye's natural offset (kappa angle)—can improve visual quality for people with nearsightedness. About 224 participants will receive either standard SMILE or SMILE with this compensation. Re…

This study tests if a newer laser method (PRESBYOND laser blended vision) is better than standard monovision LASIK for treating presbyopia, which makes it hard to see up close as you age. About 100 adults aged 40 to 55 will be randomly assigned to one of the two surgeries. They w…

This study compares two ways of doing cataract surgery to find out which one helps people see better the day after the operation. The researchers will test a newer method that keeps the surgery inside the lens capsule, hoping it causes less damage to the eye's inner lining. About…

This study looks at whether taking a daily supplement of lutein, zeaxanthin, and meso-zeaxanthin (natural pigments found in plants) can improve contrast sensitivity—the ability to see subtle differences in light and dark—in healthy Chinese adults aged 35 and older. Over 12 months…

This study tests whether one session of AI-assisted structured guidance can improve the quality of narrative literature reviews written by medical postgraduate students. 102 students will be randomly assigned to either receive the guidance session or use AI freely without it. The…

This study tests different doses of alfentanil (a painkiller) combined with propofol (a sleep medicine) to find the best amount for placing a laryngeal mask airway in children aged 7 to 12. The goal is to make the procedure smoother and safer. Forty children having day surgery wi…

This study will follow 421 people with keratoconus, a condition that thins and bulges the cornea, to learn how it progresses and what factors increase risk. Researchers will use eye exams and imaging to track changes over time. The goal is to improve how doctors manage the diseas…

This study will check the eyes of 3,000 people in Xinxing County, including schoolchildren, seniors, and people with diabetes. The goal is to measure how common vision problems like nearsightedness and cataracts are, and how well they are being treated. Participants will have sim…