Laser eye surgery gets a precision upgrade: new trial tests alignment fix for sharper vision

NCT ID NCT07512115

Recruiting now Symptom relief Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jul 08, 2026 · Updated 3 times

Summary

This trial tests whether a small adjustment during SMILE laser surgery—compensating for the eye's natural offset (kappa angle)—can improve visual quality for people with nearsightedness. About 224 participants will receive either standard SMILE or SMILE with this compensation. Researchers will measure visual distortions and clarity over six months to see if the adjustment makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: SMILE laser surgery with kappa-angle compensation
What this could lead to: If successful, this could lead to better visual quality and fewer visual distortions after laser eye surgery for people with myopia.
What could go wrong: This is a small, early-stage trial with 224 participants, so results may not apply to everyone. The improvement may be minor and not noticeable in daily life.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

myopia refractive error

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MYOPIA REFRACTIVE AMETROPIA

Contacts and locations

Locations

Zhongshan Ophthalmic Center
RECRUITING

Guangzhou, Guangdong, 510060, China

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